short chain fatty acids การใช้

• A possible mechanistic explanation linking gut flora to obesity involves short chain fatty acids.
• In contrast to polysaccharides, humans can use short chain fatty acids as a source of energy.
• Lactulose is metabolized in the colon by bacterial flora to short chain fatty acids including lactic acid and acetic acid.
• Humans are unable to digest complex polysaccharides and rely on gut microbiota to ferment these polysaccharides into short chain fatty acids.
• The name is used as part of the name of esters and salts of butyric acid, a short chain fatty acid.
• :As mentioned here, fibers are converted by gut bacteria to short chain fatty acids and other compounds that our bodies need.
• *The bovine rumen harbors a complex microbiome that converts plant cell wall biomass into proteins, short chain fatty acids, and gases.
• Some anaerobic fermenting microbes in the rumen ( and other gastrointestinal tracts ) are capable of degrading organic matter to short chain fatty acids, and hydrogen.
• Acetic acid is essentially a very short chain fatty acid ( it doesnt have enough carbon to make it aliphatic, but it undergoes the same chemistry ).
• Starchy plants, in particular, are a main source of resistant starch  an important dietary fiber with strong fermented and metabolized by gut flora into short chain fatty acids, which are well known to offer a wide range of health benefits.
• People with 3-hydroxyacyl-coenzyme A dehydrogenase deficiency have inadequate levels of an enzyme required for a step that metabolizes groups of fats called medium chain fatty acids and short chain fatty acids; for this reason this disorder is sometimes called medium-and short-chain 3-hydroxyacyl-coenzyme A dehydrogenase ( M / SCHAD ) deficiency.
• In addition, research in rodents has indicated that the abundance of short chain fatty acids in the gut can affect the blood levels of gut hormones such as GLP-1, GLP-2 and peptide YY . These changes in gut hormone levels have shown to affect glucose tolerance, insulin signaling, intestinal barrier function and have led to weight gain in rodents.
• Diener-West has also co-published a paper concerning the treatment of cystic fibrosis entitled " Evidence of CFTR function in cystic fibrosis after systemic administration of 4-phenylbutyrate . " The study investigated the effects of an orally bioavailable short chain fatty acid called 4-phenylbutyrate, which " modulates heat shock protein expression and restores maturation of the deltaF508 [ a mutation linked to cystic fibrosis ] protein in vitro and in vivo, " when given to subjects with cystic fibrosis.